18.1. Vitamin K
Vitamin D is likely synergy with vitamin K supplements where the two share several mechanisms of cardiovascular and metabolic bone work. [294]
18.2. Calcium
Means are the individuals who suffer from serum levels of 86.5 nmol / l 65% better than calcium people with average serum levels of absorption of 50 nmol / L [295]
19. The safety and toxicity
19.1. Kidneys
And found a meta-analysis that examined the relationship between vitamin D and mortality (which was seen to drop mostly at older women) that there is an increased risk of nephrolithiasis (kidney stones), when the vitamin D combined with calcium supplements, with RR 1.17 and CI 1,02- 1.34 from a sample of 74789. had seen all of [296] and an increased risk of kidney stones and decreased mortality rates only with vitamin D3 supplements. [296]
19.2. Squamous dysplasia
High levels of vitamin D in the blood have been associated with esophageal squamous dysplasia, [297] As noted by the study take cross-sectional study of 720 participants in China that people with abnormal growth and circulating levels of vitamin D 36.5nmol / L while those without 31.5nmol / L dysplasia and the highest quarter have relative risk 1.86, compared with at least a quarter. [297]
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